Abstract

Study Design:Randomised clinical trial.Purpose:Comparison of ocular hypertensive response of 3 commonly used steroids for managing postcataract surgery inflammation.Methods:Patients were divided into three groups of 50 each.Group A-received topical dexamethasone0.1%,Group B received topical prednisolone1% and Group C received topical difluprednate0.05% four times a day for six weeks after cataract surgery.IOP was recorded preoperatively, on first postoperative day and at the end of first, third and sixth week.Results: The mean age was 64.4±9.39 years, 48% were males. Mean IOP in the three drug groups was not statistically significant at 1st week, 3rd week and at 6th week after cataract surgery. 3 patients in difluprednate group developed significant rise in IOP.Conclusion: all three steroids were equally safe and did not cause any significant rise in IOP over six-week period.Higher values were noted in difluprednate group at the end of first and third week after cataract surgery.