Abstract

Purpose: Ocular manifestations in psoriasis are due to psoriatic plaques or psoriasis‑related immune‑mediated inflammatory processes. We evaluated ocular changes associated with moderate-to-severe psoriasis.
Methods: In this prospective cohort study, psoriasis patients with PASI score of more than 10 were included. The OSDI
score, Schirmer’s score, TBUT, corneal and conjunctival staining score were noted. All these parameters were re‑evaluated at 8 weeks of follow‑up .
Results: 50 patients were enrolled in the study. Most common ocular pathologies were tarsal hyperemia and anterior blepharitis in 94.% and 48% eyes, respectively. Mild, moderate, and severe dry eyes were seen in 20%, 10%, and 26% eyes, respectively. In 16 patients evaluated on follow‑up at 8 weeks, cornea and conjunctiva’s ocular surface staining score increased and TBUT decreased significantly.
Conclusion: Screening patients with greater severity of psoriasis would help in early management of such problems.