Abstract

Study design: Retrospective
Purpose: Quantitative assessment of peripheral choroidal vasculature on UWF ICGA in posterior uveitis.
Methodology: Early and mid-phase FFA ICGA images were used to analyze (using affine registration and advanced image processing techniques) various choroidal vascular parameters. Choroidal vessel densitometry (CVD), asymmetry of choroidal outflow (ACO), the diameter of the prominent choroidal vessel, and distance between the ampulla and optic nerve were assessed in eyes with posterior uveitis and in the control group.
Results: A total of 31 cases and 14 controls were included. The CVD in posterior uveitis was significantly lower than the control group. The ampullas in posterior uveitis were located significantly closer to the optic nerve compared to the control group in all four quadrants. Other parameters were comparable in both the groups.
Conclusion: CVD and ampulla location were significantly altered in uveitis eyes as compared to the control group.