Abstract

PURPOSE: To evaluate the etiology and clinical profile of patients
diagnosed with toxic and nutritional optic neuropathy.
METHODOLOGY: It is a prospective observational study where patients were grouped as toxic optic
neuropathy with or without nutritional deficiency and nutritional optic
neuropathy based on history, clinical and laboratory findings and were
treated accordingly. Best Corrected Visual Acuity(BCVA), colour
vision,central fields and fundus were noted and followed up after 3
months.
Results: Out of 45 patients(31 males and 14 females) with a median age
of 41 years, 86.6% had toxic optic neuropathy,4.4% had toxic optic
neuropathy with nutritional deficiency and 8.9% had nutritional optic
neuropathy. On diagnosis and subsequent treatment , BCVA improved
from a median baseline of 6/18 to 6/12 after 3 months .Colour vision ,
fundus and central fields also showed statistically significant
improvements ( p < 0.05) at the third month follow up

Full Text