FP0585 : Eyes on the unseen: Lung adenocarcinoma presenting as iris and ciliary body metastasis

Abstract

A 65-year-old male was referred for the left eye irido-ciliary body mass for further evaluation. The left eye had a small, well-circumscribed, white gelatinous, amelanotic mass noted temporally in the angle with a filiform appearance. The ultrasound biomicroscopy showed a large hyperreflective mass at 3 o’clock in the ciliary body, the anterior chamber, the angle, the iris, anterior surface of the lens. The patient was taken up for iridectomy and the sample was sent histopathology with immunohistochemistry. The histopathological examination identified that the tumor was composed of malignant cells forming glandular structures alongside papillary projections. Immunohistochemical tests showed positive results for CK (AE1/AE3). The diagnosis was a poorly differentiated adenocarcinoma was made. A whole-body PET scan and CT was done. The imaging features were suggestive of primary bronchogenic malignancy of the right lung with systemic metastases. The lung biopsy confirmed the diagnosis.

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