Abstract

The aim of this prospective, interventional study of 2 years duration was to assess the clinical outcomes of lacrimal gland botulinum toxin injection in patients of inoperable epiphora or patients who deny surgery for epiphora, to assess patient response and satisfaction and to check for complications post-treatment. Study was conducted on patients presenting with complaints of epiphora to the OPD , who met the inclusion and exclusion criteria. Botulinum toxin injection (Clostridium Botulinum type A neurotoxin complex) 0.1 ml was given in the palpebral lobe of the lacrimal gland. A total of 40 eyes have been studied to analyze the clinical outcomes of botulinum toxin injections by comparing parameters pre-injection and post-injection. There was a significant reduction in pre and post-injection Schirmer I and Munk scores at 1 and 3 months. Subjective satisfaction level was also assessed which showed a majority of cases having complete resolution with no permanent complications.