Abstract

Objectives: To Evaluate NLR, PLR, and MLR in corneal diseases and to identify the most dependable marker.
Method: Conducted a case-control study, matching corneal disease cases with healthy controls by age and gender. Performed comprehensive ophthalmic assessments, documenting findings from Slit-lamp Examination, Keratometry, and Pachymetry. Utilized Specular Microscopy and AS OCT as required. Collected venous blood samples to calculate NLR, PLR, and MLR.
Results: Among 120 participants, 35.7% were males, and 64.2% were females, averaging 62 years in age. Cases exhibited corneal opacity (64%), corneal degenerations (14%), Epithelial defects (12%), healed corneal ulcers (7%), and corneal dystrophies (2%).
Conclusion: NLR, PLR, and MLR are indicative of systemic inflammation, with higher levels in cases than controls. Notably, MLR demonstrated a significant increase, suggesting its potential as a more effective parameter for assessing inflammatory changes in corneal pathologies.

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