Abstract

To correlate the severity of meibomian gland dysfunction (MGD) with the serum lipid profile.
The study was conducted as a prospective observational study on 50 consecutive patients
diagnosed with MGD of various severity, after they gave their valid consent. Meibomian
gland status was evaluated by meibography machine ME-CHECK® for meibum quality,
expressibility, and numerical scoring. Lipid profile was done from an overnight fasting blood
sample and evaluated for total cholesterol, high- density lipoprotein (HDL) cholesterol, low-
density lipoprotein (LDL) cholesterol, and triglycerides (TGs). Patients with MGD more
more often had serum TGs >150 mg/dL, total cholesterol >200 mg/dL, an LDL >130 mg/dL,
and serum HDL >40 mg/dL. A positive association existing between increasing severity
MGD and increasing levels of all the components of lipid profiles. Guides us to further study
with effect of correction of lipid profile imbalance on severity of MGD.

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