FP2747 : TARGETED TRIUMPH: Transcutaneous Retrobulbar AmphotericinB Injection(TRAMB) for Orbital Mucormycosis

Abstract

A 34 yr old male, presented with Right Eye mild Ptosis, ocular motility restriction, mid-dilated pupil and optic disc edema. His vision was Counting Fingers 1meter with total ptosis and almost complete EOM paralysis.
Past history of delta variant of the SARS-CoV-2 virus infection and 3days ICU admission, treated with Inj Remdesivir, IV steroids, oxygen supplementation, diagnosed as suspected mucormycosis. Diabetic on Insulin since diagnosed with COVID19. Sinus debridement done elsewhere and was referred to us for orbital exenteration in view of the rapidly deteriorating ocular status and apical disease with a threat to cerebral involvement. He was on Inj Amphotericin B and Tab Posaconazole.
Imaging revealed an area of necrosis in the posterior orbit. He underwent multiple localized orbital debridements and TRAMB injections along with Oral and IV antifungals.
He regained a visual acuity of 20/20 will full ocular motility and resolution of ptosis with life, eye and vision salvage.

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