Abstract

Infectious keratitis is a known rare complication of collagen cross linking with a reported incidence of 12 per 1000 cases. Effectiveness of CXL in treating nonresolving microbial keratitis with superficial stromal involvement has already been proven , however it is interesting that CXL itself might be a precipitating factor in causing keratitis.
We discuss an interesting case of a 30 year old boy who developed perforation and corneal infection post PRK with C3R done elsewhere and how it was managed medically, then Glue-BCL and ultimately with therapeutic keratoplasty. Interestingly the patient already had a history of C3R with PRK in his other eye 1.5 years back which had also perforated and was managed with glue BCL. Good and timely microbiological workup of these patients is crucial in the treatment of these patients.