Abstract

Aim:To determine effect of Trabeculectomy on peripapillary vessel density&ONH perfusion using Optical Coherence Tomography AngiographyMethods: Prospective,observational study.67 patients withPOAG(n=25)&PACG(n=42),who underwent trabeculectomy were included.OCT-A scans were performed using AngioPlex™ CIRRUS™ HD-OCT 1 week before&1,3,6 months postop. Changes in Peripapillary vessel density(pVD) ,Perfusion index, Flux index,RNFL,GCL-IPL were analyzed. Correlation with IOP&factors associated with changes in Pvd was evaluatedResults:pVD in all quadrants showed significant improvement,sup(p= 0.016,p=<0.001) inf(p< 0.001,p<0.001),nasal(p < 0.001,p < 0.001), temporal(p=0.009, p<0.009) in both grps after trabeculectomy.There was significant increase in PI(p=0.022, p=0.004)in both grps & FI in POAG(p<0.001).There was no significant correlation between IOP&change in pVD.Conclusion: OCT-A demonstrated a significant improvement in microvascular parameters after trabeculectomy in both POAG& PACG