Abstract

DESIGN- Cross sectional study
PURPOSE- Comparison of retinal microvasculature changes in amblyopic, fellow, healthy control eyes.
METHODS- All patients underwent complete ophthalmological examination and OCT and OCTA imaging. Central Macular thickness (CMT),peripapillary retinal nerve fibre layer (RNFL)thickness ,foveal avascular zone (FAZ) size,vascular density percentage (VD) in the superficial and deep capillary plexus (SCP1, DCP1) at 1.5 mm and 3 mm (SCP2, DCP2) scans were measured and compared between groups.
RESULTS-CMT and FAZ size was greater in amblyopic and fellow eyes as compared to control eyes however difference between the 3 groups was not statistically significant. SCP1 values in inferior and nasal quadrants and DCP1 values in the superior,nasal, and temporal quadrants were significantly lower in amblyopic and fellow eyes as compared to control eyes.
CONCLUSIONS- These vascular changes could shed further light in etiology of amblyopia and its prognosis in future.