Abstract

CASE REPORT: 13 year female patient presented with gradual progressive diminution of vision in right eye.H/o similar complaints in the left eye.VA IN RE-CF1M,LE-6/6.MRI Brain-Right optic nerve: T2/FLAIR hyperintensity with post contrast enhancement in right posterior half of infraorbital part of optic nerve upto the chiasm-Features s/o optic neuropathy.MRI Spinal cord-Normal.RE- RAPD+.Serum Aquaporin – 4 NMO positive.
TREATMENT:The patient was started on Prednisolone 1 mg/kg(30mg) PO daily for 1 month, tapered over 3 TO 6 months and Azathioprine 50 mg PO,OD for 2 yrs.Inj Rituximab 500mg 2 injections given 15 days apart.
DISCUSSION:NMOSD is an autoimmune chronic inflammatory disease of CNS system characterized by acute, severe episodes of optic neuritis and longitudinally extensive transverse myelitis (LETM),with a relapsing course.
CONCLUSION:High index of suspicion of this rare disease is required to avoid delayed diagnosis and treatment.