Abstract

Vogt-Koyanagi-Harada (VKH) disease, a bilateral granulomatous panuveitis, can be diagnostically challenging, particularly in the absence of typical extraocular features. We present the case of a 36-year-old male who experienced abrupt, painless vision loss in the right eye. Despite a history of obsessive-compulsive disorder and a three-year medication regimen, ocular examination revealed optic disc edema and serous retinal detachment inferotemporally, suggesting VKH. Elevated ESR, CRP levels, and a positive Mantoux test provided further diagnostic support. Treatment with oral and topical steroids led to vision improvement. This case underscores the diagnostic intricacies of VKH and highlights the importance of a comprehensive evaluation. It emphasizes the need for recognition of diverse clinical presentations to ensure a timely diagnosis and effective management.