Abstract

Purpose: This study aims to assess impact of lenticular profiles in various laser-assisted lenticular extraction surgeries (LALEX) on corneal nerve regeneration and its impact on outcomes.
Methods: In-vivo confocal microscopy was done to evaluate corneal nerve changes in eyes undergoing LALEX with ELITA SILK, SCHWIND ATOS(SS), and SMILE procedures(n=42 each). Corneal nerve fiber density (CNFD) and corneal nerve fiber length (CNFL) were assessed using CCMetrics software. Changes in parameters from pre to postoperative stages were compared.
Results: Preoperative CNFD and CNFL were similar in all 3 groups. Change in CNFD and CNFD was significantly less in SILK and SS groups compared to SMILE at 1, 3 and 6 months postoperatively.
Conclusion: The SILK and SS groups showed a reduced change in CNFD and CNFL, indicating less nerve damage and faster nerve regeneration. This suggests that these procedures may lead to quicker recovery of ocular surface balance and reduction in dry eye symptoms

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