Abstract

Purpose: To analyse the microbiological spectrum and antibiotic sensitivity in children with CNLDO and determine the empirical drug of choice.
Methods: Prospective study included 198 eyes of 170 patients aged 0-5 years with CNLDO. Conjunctival swab after applying pressure over the lacrimal sac were sent for microbiology. Antibiotic susceptibility testing was done by Kirby Bauer disc diffusion method.
Results: 94.94 % samples were culture positive, 48.4% were Gram positive. Most common Gram positive and Gram negative organisms isolated were S.pneumoniae and H.influenza respectively.
Gram positive organisms showed highest sensitivity to chloramphenicol and Gram negatives to
amikacin. Both isolates were susceptible to ofloxacin and gatifloxacin.
Conclusions: There was a Gram positive predominance in CNLDO. Fluoroquinolone topical drops
can be used in the treatment of cases with CNLDO

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