Abstract

STUDY DESIGN: Prospective, non-randomized, non-interventional study done in OPD of a tertiary eye center
PURPOSE: To evaluate and compare FAZ changes in diabetic eyes using OCTA (both, SCP & DCP ) and FFA(SCP only) over one year and to correlate these with the progression of diabetic retinopathy.
METHODS:Three groups of diabetics were studied over 12 months with exam at 0, 6 and 12 months. Group 1 (eyes with no DR), group 2 (eyes with DR but no DME), group 3 (eyes with DR and DME). OCTA images of DCP were marked using IMAGE J software after setting scale to 1024×1024 pixels in a 3×3 mm scan area. SCP was marked using the in-built Angioplex OCT tool. FAZ on FFA was manually outlined using the in-built Visupac freehand measuring tool.
RESULTS: Significance was noted at baseline, 6 months, and 12 months, on comparing group 2 with group 3, and group 1 and group 3 for both SCP and DCP. FAZ area was greater with more severe diabetic retinopathy (groups 2&3) at both 6 and 12 months.