Abstract
Objective: To study the computational and mathematical modelling of ocular cancers
Methods: Observational and laboratory based study. 15 cases of pathological samples were retrospectively studied from frozen sections, permanent sections, enucleated globes by different microscopy (Gross: LEICA 6SD and Compound microscope: Zeiss, Axioskop 40-Axiocam MRc, Germany) and documented by single ocular pathologist. All the specimens were sent to laboratory after surgery with proper consent.
Results: (n=5) sebaceous gland carcinoma, (n=2)squamous cell carcinoma, (n=3) choroidal melanoma and (n=5) retinoblastoma cases were taken in the cohort. Local high risks and metastatic potential were explored in these models. Geometric progressions were analysed.
Conclusion: Current challenge is to understand the mechanism of tumour advancement and shape for the future research in ocular tumour biology.