Abstract

Study Design:A retrospective case control study.Purpose: To understand the pathophysiology and characteristics of an inclusion cyst in a case of Stevens-Johnson syndrome, along with its correlation to severity of the disease.Methods: Patients with Stevens-Johnson syndrome who presented with inclusion cysts as cases and 40 eyes with SJS as controls over the past 23 years. The severity of the disease was graded using the SOTOZONA grading scale.Results:A total of 24 eyes from 21 patients and 40 eyes of SJS patients were assessed, with an average age of 30 years.Sotozono severity grading indicated a higher prevalence of lid complications compared to corneal or conjunctival complications which was similar to controls.Fornicial conjunctival location was more coomon, appearing as pink oval masses. Majorly of them were treated with surgical excision with 33% having histopathological confirmation and no recurrence seen in 33 month follow up.