FP2898 : Incidence and clinical outcomes following Diffuse lamellar keratitis (DLK) post SMILE.

Abstract

In this retrospective study, total of 1313 eyes were analyzed, where patients underwent SMILE, presenting with signs of DLK were included. Incidence,management, clinical outcomes after resolution were recorded. Uncorrected distance visual acuity (UDVA), Corrected distance visual acuity (CDVA) and Objective scatter index (OSI) were monitored from presentation till resolution. Incidence of DLK was 1.37 % with mean presentation time 2.72 days. Of 18 eyes, 11 eyes of grade 1 DLK were managed by topical steroids and the rest 7 eyes of grade 2 DLK were treated by an interface wash. Mean UDVA and CDVA was 0.18 ±0.16 and 0.16 ±0.17 LogMAR, that improved to 0.01 ±0.14 and -0.03 ±0.10 LogMAR by the end of resolution, (p<0.001). The mean resolution time was 8.94 days. Mean laser energy used was 26.33±1.71nJ, which showed a positive correlation with OSI on POD1 (p<0.05). DLK post SMILE, when recognised and managed early, results in satisfactory outcomes with no permanent effects on visual acuity.

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