Abstract

To report a cohort of patients with Stargardt’s disease having punctate inner choroidopathy (PIC) like retinopathy on OCT and correlate with best corrected visual acuity (BCVA)
This was a retrospective study where patients having Stargardt’s disease with OCT scans were included. PIC like retinopathy was defined as focal, hyperreflective lesions splitting the retinal pigment epithelium/Bruch membrane (RPE/BrM) complex on OCT. Patients’ demographics, imaging features and BCVA were analysed
88 eyes of 44 patients were included (66% males; mean age 26.84 years) with mean BCVA of 0.58. PIC like retinopathy was seen in 45 eyes (51.1%) in a 9mm*9mm OCT scan. Five eyes (11.1%) had PIC like retinopathy within 500µ of fovea with mean BCVA of 0.76, which was significantly lower as compared to patients without such retinopathy
Damage to RPE cells in Stargardt’s disease causes RPE/BrM disruption triggering a PIC like retinopathy. If present within 500µ of fovea, leads to poorer visual acuity