Abstract

Purpose:
The study was undertaken to look into the clinicodemographic profile, management and clinical outcomes in advanced retinoblastoma at a tertiary care center.
Methods:
A prospective cohort study was conducted for four years and during this period 42 patients of intraocular advanced retinoblastoma were assessed.
Results:
The mean age of the study group was 13 months. The most common presentation was leukocoria with diminished vision. Most of the patients had group E retinoblastoma as per international classification of retinoblastoma. In 12 patients with group E retinoblastoma, primary enucleation was performed and in 06 patients secondary enucleation was done. In 30 patients, globe salvage treatment was attempted and we could manage to save 23 eyes.
Conclusion:
The current study has shown that globe salvage is possible in advanced retinoblastoma if appropriate therapy is instituted depending upon the extent of the tumor and availability of latest treatment modalities.

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