FP1959 : Role of OCT biomarkers and systemic inflammatory index in Type 2 diabetes

  • Chief AuthorDr.Soumya H.V.
  • Co Author : Dr.Amrutha Aravindakshan, Dr.Darshan S M, Dr.Pratheek Prabhu
  • Presenting Author : Dr.Poojitha S

Abstract

Study design: Case control study
Aim: To determine the correlation between OCT biomarkers and systemic immune inflammatory index (SII) in diabetic retinopathy
Methods: 30 diabetic patients with varying grades of retinopathy and 30 diabetic controls were evaluated for visual acuity, anterior segment examination, fundoscopy and OCT. Systemic inflammatory markers like SII, neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) were calculated and compared with OCT biomarkers including hyperreflective foci, intraretinal cyst, disorganization of retinal inner layers (DRIL) and sub-retinal fluid (SRF)
Results: According to the ROC curve, the AUC of SII is 0.760. The cut-off point for presence of DR by SII is 608.2132 with sensitivity and specificity of 65.4% and 75% respectively
Conclusion: It was found that patients with diabetic retinopathy showed a higher value of SII and among the OCT biomarkers, hyperreflective foci (HRF) was found to significantly correlate with SII.

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