Abstract

Purpose: To compare the pupil size of patients having migraine with photophobia vs normal subjects and to evaluate the role of photochromatic glasses in reducing MIDAS scores.
Methods: 100 eyes of 50 patients who had migraine with photophobia were compared with same number of normal subjects. The pupil size was measured with IOL Master 700 and MIDAS scores obtained. Photochromatic glasses were prescribed to all patients of migraine with photophobia and the MIDAS scores were calculated at the end of 3 months.
Results: The mean pupil size was 4.89 mm +/- 0.9 mm (95% CI) in patients of migraine with photophobia as compared to 3.8 mm +/- 0.49 mm (95% CI) in normal subjects with a p value of <0.0001 . 90% patients who used photochromatic glasses had a reduction in the MIDAS scores whereas 10% had no change.
Conclusion: The pupil size in patients of migraine with photophobia is larger as compared to normal subjects and photochromatic glasses can help reduce the migraine related disability.