Abstract
Purpose:A Prospective observational study to determine the prevalence and clinical features of bacillary layer detachment(BALAD) in patients of DME and to determine treatment response to antiVEGF.
Material and methods:. A total of 33 treatment-naïve eyes with centrally involved DME that underwent anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections on PRN basis. With minimum follow up for 6 months BALAD was found in 7.2% of eyes with concurrent subretinal fluid (SRF). All eyes were divided into 3 groups: group that had neither SRF or BALAD; the SRF only group had SRF but no BALAD; and the BALAD group had both SRF and BALAD.
Result: A significant increase in baseline central macular thickness in the BALAD group was observed.
Conclusion: Total resolution of BALAD was noted after anti-VEGF therapy, along with a significant decrease in CFT in all groups. Eyes with BALAD tended to have the worst baseline visual acuity but showed the most improvement after treatment.