Abstract

Aim-To report a case of B/L granulomatous panuveitis
Casereport -A 45 year old female presented with decreased vision in BE since 2 days with inability to identify colours. H/O redness in BE.On ocular examination vision in BEwas CF-CF. Anterior segment of BE shows keratic precipitates, cells 1+ , flare 1+, Ac shallow depth. IOP was 31mmhg in RE and 36 mmhg in LE.Fundus examination showed BE hyperaemic discswelling with serous fluid filled pockets. OCT shows BE vitritis,subretinal fluid accumulation and features of choroiditis.
Discussion- VKH syndrome is a multi systemic granulomatous autoimmune disease affecting eye,CNS,inner ear and skin.VKH includes at least one finding in three out of the following B/L chronic iridocyclitis , posterior uveitis including exudative RD,disc oedema,neurological signs and cutaneous findings. VKH is seen in pigmented individuals and has a genetic link HLA-DRB1. Inflammatory signs are related to the T cell mediated response against melanocytes.