Abstract

Aim of our study was to study the role of Retrobulbar Injection of Liposomal Amphotericin B in patients with mucormycosis This was Prospective interventional study done in tertiary care hospital on 110 cases. All the cases with proven fungal invasion of orbits/orbital apex/Retrobulbar fat/Extraocular muscles or fungal Biopsy proven were administered Retrobulbar Liposomal Amphotericin B injection 3.5 mg/ml . Results -Out of 110 cases of mucormycosis included in study, 90 cases showed ocular involvement Out of this 61 cases (67%) showed improvement in ocular symptoms . 11cases (12%) had deterioration in ocular signs and symptoms despite of giving injection and thus considered for Exenteration. 18 cases (20%) were neither improved nor deteriorated . Conclusion – The patients of mucormycosis without cerebral involvement can be subjected to Retrobulbar Liposomal Amphotericin B injection can reduced the spread of the disease , conserved vision , control ocular symptoms and sparing the globe.

Full Text