Abstract

Study design :A prospective observational study. Purpose: This study validates the DIGIROP-Birth Model for Retinopathy of Prematurity (ROP) prediction. Methods: 513 infants (24-30 weeks’ gestation) were analyzed. Statistical tools included Chi-square tests, ROC curves, and gender as a significant factor. Results: DIGIROP-Birth model showed 90% sensitivity, 53.6% specificity. Males had a higher ROP risk (14.34%) than females (4.90%). The AUC was 0.718, slightly lower than in developed regions, emphasizing gender as a critical predictive factor. Conclusion: The DIGIROP-Birth Model is validated for ROP prediction. Despite slightly lower sensitivity and AUC compared to developed areas, gender emerged as a vital independent risk factor. Refinement with additional factors is recommended for improved predictive accuracy