FP1814 : Efficacy of Netarsudil eye drop in primary angle-closure disease: A randomized comparative study

  • Chief & Presenting Author : Dr.Faisal T. T.
  • Co Author : Prof. Surishti Raj, Prof.Sushmita Kaushik, Dr.Surinder S Pandav

Abstract

Purpose: To evaluate efficacy of Netarsudil 0.02% OD in comparison to Latanoprost 0.005% HS in Post-Peripheral laser iridotomy (PPLI) primary angle-closure disease (PACD) patients with inadequately controlled IOP
Method: 45 eyes of 45 PAC/mild-moderate PACG with PPLI open angles up to at least 180° and having persistent high IOP were randomized to either topical Netarsudil 0.02% (n=23) OD or Latanoprost 0.005% (n=22) HS. IOP and VA and side effects were assessed at weeks 2, 6 and 3 months
Results: Both groups were age and sex matched. The baseline IOP was comparable (24.723.37 mmHg Vs 23.302.50 mmHg, p=0.294). The IOP was significantly reduced in all follow-up visits in both the groups and the percentage reduction was also comparable among the groups (p>0.05). The conjunctival hyperemia was seen in 36.5% of eyes in netarsudil group at final follow up
Conclusion:Efficacy of Netarsudil 0.02% was comparable to Latanoprost 0.005% in mild-moderate PACDs with at least 1800 of open angles

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