Abstract

Study Design: It is a retrospective case series from a single ocular oncology center which included total of 823 consecutive patients with uveal melanoma.
Purpose: To determine the correlation of Fitzpatrick Skin Type (FST) and iris color with tumor size (tumor thickness and basal diameter) in patients with uveal melanoma.
Methods: Patients were classified into FST type I, II, and III-V and iris color (blue, green, and brown). The correlation of FST and iris color with mean tumor thickness and largest basal diameter was evaluated.
Results: A comparison of FST (I, II, and III-V) revealed differences in mean tumor thickness (p= 0.04) and largest basal diameter (p=0.006). Based on iris color, there was a difference with brown iris color relative to FST for mean tumor thickness and largest basal diameter but no difference with blue or green iris color.
Conclusions: Overall, patients with brown iris color and FST type III-V demonstrated larger tumor thickness and basal diameter.