Abstract

STUDY DESIGN: case report.PURPOSE AND METHODS: to describe a novel case of inverse RP with PIC-like retinopathy in a 36-year-old female and report its imaging and clinical correlates. RESULTS: Fundus examination showed hyperpigmented RPE changes and bone spicules and FAF showed dense hypoautofluorescent mottling at the posterior pole and peripapillary region. Peripheral retina showed a unique hypoautofluorescent lacy pattern. Structural OCT of both eyes showed hump-shaped nodules with homogeneous moderate reflectivity centered at the photoreceptor layer, retinal pigment epithelium/bruch membrane (RPE/BrM) discontinuities with posterior choroidal hypertransmission. ERG showed extinguished photopic and scotopic responses. CONCLUSION: PIC-like lesions have been described in a few retinochoroidal diseases unrelated to PIC but never in inverse RP. Thus, we report PIC-like lesions for the first time in a case of inverse RP.