Abstract

Purpose
To present a case of tamoxifen retinopathy on a 50-year-old woman.
Design
An observational case.
Methods
A review of history, clinical examination, and findings on Optical Coherence Tomography (SD-OCT) was conducted.
Results
A 50 year old female patient, who had been treated with oral tamoxifen after mastectomy due to breast cancer, had profound visual impairment in both eyes since 2 years. Disruption of the ellipsoid zone and interdigitation zone which represent photoreceptor damage as well as cavitation and RPE deposits was revealed on SD-OCT in both eyes.
Conclusion
Tamoxifen-induced retinopathy could be detected by SD-OCT and fundus examination. As it is irreversible, patients who are given tamoxifen need regular ophthalmic consultation, including SD-OCT and fundus examination before and during the treatment in order to early detect and avoid further retinal damage.