Abstract

Purpose:To evaluate efficacy of DMEK to treat corneal edema associated with irido corneal endothelial syndrome and report outcomes in 6 cases. Methods:In this case series, the corneal endothelium was selectively replaced by the DMEK technique in eyes with ICE syndrome. six eyes were included with 18 months follow up. At followup eyes were evaluated for graft attachment, corneal clarity, endothelial count, visual acuity.
Results: In all the six cases corneal edema was resolved and corneal clarity was maintained with no signs of graft rejection or graft detachment at last follow up. An average BCVA of logmar 0.2 was achieved and maintained. An average 18 % endothelial cell density decline was noticed comparable to DMEK in normal eyes.
Conclusions: DMEK can successfully treat corneal edema and associated visual loss caused by ICE syndrome with similar predictable results as DMEK in normal eyes.