Abstract

Study design- Retrospective study
AIM- To evaluate the potential role of hyperreflective foci (HF) as a prognostic indicator of visual outcome in patients with macular edema (ME) due to retinal vein occlusion (RVO).
Method- 77 eyes of 77 patients with ME due to central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO) who were treated with anti-vascular endothelial growth factor (anti-VEGF). All patients underwent baseline investigation, OCT and follow-up. . Multiple linear regression analysis was used to analyze the data.
Results- Among two groups, mean age in BRVO 54.37±12.34 and in CRVO 53.03±12.27. At all the periods of observation (0, 30 & 90) Logmar values of ELM disrupted cases were found to be significantly higher than those with ELM intact.
Conclusion- The presence of HF in outer retina layer (ORL) and ELM status are prognostic factors associated with the final BCVA in patients with ME due to RVO after anti-VEGF treatment.