Abstract

Methods:Eleven patients with macular edema more than 300 microns secondary to non infectious
uveitis were included in the study. A single LD-SCTA (0.5 ml) injection was performed in the
study eye with the help of a novel suprachoroidal microneedle.study parameters were noted at 4 and 12 weeks

Results: Ten of eleven patients had a significant decrease in central macular thickness (CMT). The mean CMT measurement at baseline was 513.6±191.73 μm for the ten patient who responded to the treatment, reduced significantly to 265.1±34.72 μm (p<0.003) and 260.6±34.72 μm (p<0.002) at 4 weeks and 12 weeks respectively. The mean best corrected visual acuity at baseline was 0.84±0.41 logmar unit which improved t o 0.52±0.33 (p<0.001) and 0.25±0.22 (p<0.000)at week 4 and 12 respectively.
Conclusions:Single LD-SCTA injection is efficacious in reducing CMT in macular edema, improving BCVA
and controlling the inflammation in non infectious posterior uveitis